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Anaphylaxis

  • Sx

    • acute dyspnea, angioedema, urticaria
  • Px

    • general and respiratory distress
  • Tx

    • epinephrine 1:1000 0.3-0.5 mg IM q5min prn for dyspnea
    • IV saline 1-2L for hypotension
    • steroids (prednisone 60 mg PO. If severe use methylprednisone 126mg IV)
    • diphenhydramine 50 mg IV
    • if asthma or wheezing, give albuterol 2.5mg neb
    • discharge if asymptomatic for 4 hours. Admit if unstable.
    • discharge meds: diphenydramine, prednisone taper, epi-pen
  • Pediatric dosings

    • epinephrine 0.01 mg/kg
    • saline 10-20 mL/kg
    • prednisone 2 mg/kg PO, methylprednisone 2 mg/kg IV
    • diphenhydramine 1 mg/kg

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