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Thrombocytosis

  • Criteria

    • plt > 400k
  • Ddx

    • physiologic
      • pregnancy, childbirth
      • stress, exercise
    • reactive thrombocytosis
      • malignancy
        • carcinoma
        • lymphoma (lymphadenopathy)
        • leukemia
      • iron deficiency (fatigue, pallor, pika)
      • acute hemorrhage
      • drugs, vincristine
      • rebound thrombocytosis (B12 therapy)
      • post-splenectomy
      • infection (fever)
        • TB
        • osteomyelitis
        • endocarditis
        • rheumatic fever
      • inflammation [high ESR]
        • RA
        • sarcoidosis
        • UC
        • temporal arteritis
        • Wegener's
    • myeloproliferative
      • leukemia, CML (fever, wt loss, nightsweats)
      • MM (bone pain)
      • myelofibrosis
      • polycythemia vera (headache, pruritus esp after showering)
    • other
      • essential thrombocythemia

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    Disclaimer: MDHero Workups is for educational use only, and is not meant to replace the clinical judgement of a professional. We do not guarantee the accuracy of any information on this website.