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AP elevation

  • Ddx

    • bone (bone pain)
      • healing fracture
      • Paget's disease
      • normal growth (child, teenager)
      • osteogenesis imperfecta
      • Rickets, osteomalacia
      • vitamin D usage
      • McCune albright, osteitis fibrosa cytica
    • bone cancer
    • liver (severe ALT, AST elevation)
      • hepatitis (travel hx)
      • EtOH (AST > 2x ALT)
      • cirrhosis
      • steatohepatitis
      • drugs (acetaminophen)
      • shock liver (recent shock)
      • hemachormatosis
      • alpha 1 antitrypsin deficiency (lung dz)
      • Wilson disease (neuro sx)
      • HCC
    • biliary (elevated bilirubin and AP)
      • cholestasis (RUQ pain, jaundice)
      • PBC (jaundice, pruritus)
      • PSC (jaundice, pruritus, PMH of UC)
    • biliary cancer
    • other
      • pancreatitis (epigastric pain) [lipase]
      • pregnancy
  • Labs

    • amylase, lipase
    • bone scan
    • US
    • ERCP

  • Print | Citations

    Disclaimer: MDHero Workups is for educational use only, and is not meant to replace the clinical judgement of a professional. We do not guarantee the accuracy of any information on this website.